Photo by Erdem Yücel

Hotels in Pythagorio

your current months are January, 2025 and February, 2025.
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Where to stay in Pythagorio?

Casa Cook Samos
Building design

Casa Cook Samos

5.0 star property
9.4 out of 10, Exceptional, (65)
Casa Cook Samos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Pythagorio

Pythagoreion

If you're planning a bit of sightseeing during your trip, head to Pythagoreion— just one of the monuments in central Pythagorio.

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Pythagoreion

Learn more about Pythagorio

Notable for its seaside, Pythagorio features attractions such as Samos Pythagorion Archaeological Museum and Pythagoreion.

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Photo by Erdem Yücel
Open Photo by Erdem Yücel

Frequently asked questions

Can I book a refundable hotel in Pythagorio?
If you need the flexibility to change your travel plans to Pythagorio, most properties offer refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay with my pet in Pythagorio?
Your furry friend can stay with you at these pet-friendly hotels: Casa Cook Samos, Doryssa Boutique Hotel and Naftilos. There are 5 alternatives you can choose from on our site.
Which Pythagorio hotels do our guests like for their terrific location?
Our guests rave about the location of Sunrise Hotel.
Where can I stay in Pythagorio if I want a vacation home instead of a traditional hotel?
Browse 6 vacation homes on our site. In addition, you can choose from 16 apartments.
Where can I stay if I'm visiting Pythagorio with my family?
Parents traveling with children may want to consider Casa Cook Samos, Doryssa Seaside Resort and Proteas Blu Resort - Adults Only.
Where should I stay in Pythagorio for a getaway with my partner?
Casa Cook Samos, Doryssa Seaside Resort and Proteas Blu Resort - Adults Only are great options for a romantic getaway.
Where should I stay in Pythagorio if I'm looking for a luxury hotel?
Experience luxury when you stay at Casa Cook Samos, Doryssa Seaside Resort and Doryssa Theorem Hotel.
What will the weather in Pythagorio be like during my trip?
August and July are typically the warmest months in Pythagorio when the average temp is 77°F. January and February are the coldest months when the average temperature is 55°F. January and December are the months with the most rain.
Why should I book my Pythagorio hotel with Hotels.com?
There are lots of reasons to book your Pythagorio trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.