Hotels in Main Street Hyannis

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Where to stay in Main Street Hyannis?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Main Street Hyannis

Learn more about Main Street Hyannis

Main Street Hyannis is applauded for its cultural attractions such as John F. Kennedy Hyannis Museum and Cape Cod Baseball Hall of Fame. This beachside city's sights include Wackenhammer's Clockwork Arcade and visitors speak highly of the local seafood restaurants.

Frequently asked questions

Where can I get free parking at my hotel in Main Street Hyannis?
Park your car for free at these properties: Americas Best Value Inn & Suites Hyannis Cape Cod, Cape Cod Inn and Courtyard Resort Hyannis, a VRI resort. There are 6 choices you may want to check out on our site.
Can I book refundable hotels in Main Street Hyannis?
If you want the flexibility to change your plans to Main Street Hyannis, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Main Street Hyannis hotels do guests like for their central location?
Our guests rave about the location of these properties: Americas Best Value Inn & Suites Hyannis Cape Cod and Hyannis Plaza Hotel.
Where should I consider staying in Main Street Hyannis if I'm looking for a reasonably priced accommodation?
Hyannis Plaza Hotel is an accommodation you might want to consider that’ll save you money.
Where can I stay in Main Street Hyannis if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 9 vacation homes.
Where can I stay if I'm traveling to Main Street Hyannis with my children?
Parents traveling with children may want to consider Americas Best Value Inn & Suites Hyannis Cape Cod.
Where should I stay in Main Street Hyannis for a getaway with my partner?
Hyannis Plaza Hotel is a great option for a romantic getaway.
Where should I stay in Main Street Hyannis if I want a luxurious hotel?
An option for a luxury stay is Hyannis Plaza Hotel.
What will the weather in Main Street Hyannis be like during my visit?
The warmest months in Main Street Hyannis are usually August and July with an average temp of 67°F. February and January are the chilliest months when the average temp is 37°F. The rainiest months are October and December.
Why should I book my Main Street Hyannis hotel through Hotels.com?
There are plenty of reasons to book your Main Street Hyannis travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.