Hotels in Southern Minnesota

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Free cancellation

Flexible bookings on most hotels*

Where to stay in Southern Minnesota?

Top neighborhoods in Southern Minnesota

Find out more about Southern Minnesota

Frequently asked questions

What accommodations do travelers like in Southern Minnesota?
Round Barn Farm B & B Event Center, Hilton Rochester Mayo Clinic Area and Alexander Mansion Bed and Breakfast are all properties that our guests really like.
Can I book refundable accommodations in Southern Minnesota?
If you’re looking for the flexibility to change your travel plans to Southern Minnesota, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Southern Minnesota hotels do our guests like for their terrific location?
Our guests rave about the location of these properties: Kahler Inn and Suites - Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S. For a quiet locale, travelers like Best Western Rochester Hotel Mayo Clinic Area/St. Mary’s.
Where should I consider staying in Southern Minnesota if I'm looking for a cheap accommodation?
AmericInn by Wyndham Mankato Event Center, Med City Hotel & Suites and Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel are a few accommodations you might want to consider that’ll save you money. You can browse more choices on our site, including 32 motels.
Where can I stay in Southern Minnesota if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, review our selection of 412 vacation homes. In addition, there are 131 apartments and 48 condos.
Why should I book my Southern Minnesota accommodation with Hotels.com?
There are plenty of reasons to book your Southern Minnesota travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee makes sure you always get the lowest price, and our Rewards Program lets you earn reward nights and save cash.

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