Photo by Bill Eaker

Hotels in Muscatine

your current months are January, 2025 and February, 2025.
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February 2025

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Where to stay in Muscatine?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Muscatine

Learn more about Muscatine

Muscatine is well-known for its attractions such as Mississippi River and Cedar River.

Photo by Bill Eaker
Open Photo by Bill Eaker

Frequently asked questions

Can I book refundable accommodations in Muscatine?
If you want the flexibility to change your plans to Muscatine, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Muscatine?
Your furry friend can stay with you at these pet-friendly hotels: Best Western Muscatine / Pearl City Hotel, AmericInn by Wyndham Muscatine and Hampton Inn Muscatine. There are 6 alternatives to choose from on our site.
Which Muscatine hotels do travelers like for their great location?
Our guests love these properties for their convenient location: Best Western Pearl City Inn, AmericInn by Wyndham Muscatine and Hampton Inn Muscatine.
Where can I stay in Muscatine if I want a reasonably priced accommodation?
Best Western Muscatine / Pearl City Hotel, AmericInn by Wyndham Muscatine and Hampton Inn Muscatine are a few accommodations you might want to consider that’ll save you money.
Where can I stay in Muscatine if I want a vacation home instead of a traditional hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 6 vacation homes.
Where can I stay if I'm visiting Muscatine with my family?
Parents traveling with children may want to consider The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel and Super 8 by Wyndham Muscatine.
Where should I stay in Muscatine for a vacation with my partner?
Strawberry Farm Bed & Breakfast is a good option for a romantic getaway with your special someone.
Where should I stay in Muscatine if I want a luxury accommodation?
An option for a luxury stay is The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel. Additionally, browse all 6 options on our site.
What will the weather in Muscatine be like during my trip?
July and August are typically the warmest months in Muscatine when the average temp is 72°F. January and February are the coldest months when the average temperature is 30°F. June and May are the months with the most rain.
Why should I book my Muscatine hotel with Hotels.com?
There are lots of reasons to book your Muscatine trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.