Photo by Michael Schuier

Hotels in Ladys Island

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Where to stay in Ladys Island?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Ladys Island

Learn more about Ladys Island

Ladys Island is well-known for its attractions such as Sanctuary Golf Club and Coosaw Island.

Photo by Michael Schuier
Open Photo by Michael Schuier

Frequently asked questions

What hotels do travelers recommend in Ladys Island?
Guests like Quality Inn At Town Center, SpringHill Suites by Marriott Beaufort and Tru by Hilton Beaufort, SC.
Can I book refundable accommodations in Ladys Island?
If you need the flexibility to change your plans to Ladys Island, most accommodations provide refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Ladys Island if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 31 vacation homes. In addition, you can choose from 7 apartments.
Why should I book my Ladys Island hotel with Hotels.com?
There are plenty of reasons to book your Ladys Island travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.