Hotels in Cayo Guillermo

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Cayo Guillermo?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Cayo Guillermo

Frequently asked questions

What accommodations do travelers recommend in Cayo Guillermo?
Guests like Hotel Grand Muthu Cayo Guillermo, Villa Gregorio and Iberostar Daiquirí - All inclusive.
Where can I get free parking with my stay in Cayo Guillermo?
Iberostar Daiquirí - All inclusive offers the perk of free parking.
Can I book a refundable accommodation in Cayo Guillermo?
If you want the flexibility to change your travel plans to Cayo Guillermo, most accommodations provide refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay with my pet in Cayo Guillermo?
Your furry friend can stay with you at this pet-friendly hotel: Sol Cayo Guillermo - All Inclusive.
Where should I stay in Cayo Guillermo if I want a cheap accommodation?
An inexpensive option worth considering is Villa Gregorio.
Where can I stay if I'm visiting Cayo Guillermo with my children?
Parents traveling with children may want to consider Iberostar Daiquirí - All inclusive.
Where should I stay in Cayo Guillermo for a getaway with my partner?
Sol Cayo Guillermo - All Inclusive and Iberostar Daiquirí - All inclusive are great options for a romantic getaway.
Where should I stay in Cayo Guillermo if I want a luxury hotel?
An option for a luxury stay is Iberostar Daiquirí.
What will the weather in Cayo Guillermo be like during my vacation?
With an average temperature of 76°F during the coldest months, Cayo Guillermo is a great place to visit any time of year.
Why should I book my Cayo Guillermo accommodation with Hotels.com?
There are plenty of reasons to book your Cayo Guillermo travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.