Hotels in Cape Girardeau

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Where to stay in Cape Girardeau?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on 7 November 2026.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is ₹8,975
₹10,215 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is ₹9,446
₹10,657 total
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

3. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (858 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is ₹9,219
₹10,400 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Cape Girardeau I 55 East

4. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is ₹10,798
₹12,182 total
includes taxes & fees
9 Nov - 10 Nov
The Riverview

5. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (557 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is ₹10,968
₹12,429 total
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott Cape Girardeau Downtown

6. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is ₹6,801
₹7,673 total
includes taxes & fees
15 Nov - 16 Nov
Pear Tree Inn Cape Girardeau West

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (240 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is ₹9,556
₹10,781 total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau

8. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is ₹8,502
₹9,591 total
includes taxes & fees
12 Nov - 13 Nov
Drury Inn & Suites Cape Girardeau

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is ₹8,057
₹9,170 total
includes taxes & fees
16 Nov - 17 Nov
Tru By Hilton Cape Girardeau

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
The price is ₹6,708
₹8,087 total
includes taxes & fees
22 Nov - 23 Nov
Candlewood Suites Cape Girardeau by IHG

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (819 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is ₹5,612
₹6,331 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Cape Girardeau North

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, Good, (243 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Center and Show Me Center. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is ₹6,613
₹7,725 total
includes taxes & fees
8 Nov - 9 Nov
Town House Inn Cape Giradreau

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (893 reviews)
The price is ₹7,548
₹8,169 total
includes taxes & fees
9 Nov - 10 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

14. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,001 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is ₹7,512
₹7,942 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Jackson MO

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Center awaits nearby.
The price is ₹7,115
₹7,700 total
includes taxes & fees
6 Dec - 7 Dec
Comfort Suites Jackson-Cape Girardeau

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (118 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
The price is ₹9,874
₹10,748 total
includes taxes & fees
6 Dec - 7 Dec
EC Reed's Mercantile and Hotel

17. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (451 reviews)
Feel welcomed at this cozy motel with friendly service just minutes from Shawnee National Forest. Enjoy convenient perks including complimentary WiFi and parking, plus easy access to Litz Park and Lazy L Safari Park for outdoor adventures.
The price is ₹7,482
₹8,098 total
includes taxes & fees
8 Nov - 9 Nov
Town House Inn

18. Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (41 reviews)
Tucked near a train station in Makanda, this B&B offers a tranquil escape with massage services and a welcoming bar. Explore nearby Makanda Boardwalk after breakfast, then unwind on the terrace as forest sounds serenade your evening.
The price is ₹24,599
₹28,043 total
includes taxes & fees
8 Nov - 9 Nov
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Go beyond your typical stay in Cape Girardeau

When is the best time to visit Cape Girardeau?

Our prices for hotels in Cape Girardeau are cheapest in December

Price trends for hotels in Cape Girardeau

Pricing is based on two traveller single night rates
View properties in November
Currently viewing crowd sizes and weather for November.

November

High 13°C / low 4°C. Partly sunny.
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November, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

A nighttime view of a bridge with its cables illuminated against a starry sky.

Frequently Asked Questions

Can I book a refundable hotel in Cape Girardeau?

If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?

If you want a good alternative to a hotel, look over our selection of 30 vacation homes. In addition, you can choose from 20 apartments.

What will the weather in Cape Girardeau be like during my vacation?

July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.

Why should I book my Cape Girardeau hotel through Hotels.com?

There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Cape Girardeau

Discover Cape Girardeau: A Blossoming Riverfront Haven of Culture and Adventure

Nestled along the banks of the majestic Mississippi River, Cape Girardeau, Missouri, is a delightful blend of natural beauty and vibrant culture. Known for its stunning riverfront parks and blooming floral displays, this charming city invites exploration of its rich history at the Cape River Heritage Museum. Stroll through the picturesque streets, where local boutiques and cafes abound, or enjoy a leisurely afternoon at Southeast Missouri State University’s serene campus. With outdoor adventures, artistic events, and a welcoming atmosphere, Cape Girardeau is a hidden gem perfect for those seeking an authentic Midwestern escape.

4 tips for savvy savings when booking a hotel in Cape Girardeau

  1. Book for the cheapest times: The most affordable time to visit Cape Girardeau is during January, November, and December when hotel prices are lower. For a budget-friendly trip, staying for at least 2 to 3 days is recommended to fully explore the area's key landmarks and cultural attractions. Visitors can enjoy the scenic river, delve into the region's rich history, and appreciate the local university's charm. There are also delightful dining options, unique shopping experiences, and opportunities to interact with friendly locals, making it a great value for money destination for those interested in history and culture.
  2. Look for last-minute deals on Hotels.com: To discover last-minute deals to Cape Girardeau, visit the Dealsopens in new window or Last-Minute Deals section on Hotels.com, where you may find discounted rates on hotels as your travel date approaches. Consider enabling email alerts or push notifications to stay updated on flash sales and special offers, so you could find opportunities to save. Additionally, Smart Shopping is a helpful comparison tool available via the app that allows you to compare hotel prices and amenities, ensuring you're among the first to know if prices drop or rooms become available for a spontaneous getaway.
  3. Be flexible with dates: Prices can fluctuate depending on factors such as the hotel's location, star rating, and time of year, so being flexible with your travel dates could help you save on your stay in a hotel in Cape Girardeau. For those seeking distinctive accommodations, boutique hotels can provide a more personalised experience and may also offer better value. When you book through Hotels.com, we will inform you if the price for your chosen dates is above or below the average. If the price is on the higher side, we will suggest alternative dates that may be more affordable to help you find the best deal.
  4. Consider your location: Hotels near the city centre generally tend to be more expensive, but thanks to Cape Girardeau's excellent public transport links, you may discover a more affordable independent hotel a bit further out that is still well-connected. For those keen to explore alternative, less crowded neighbourhoods or even lesser-known nearby towns, there is often great value for money to be found. Opting for these alternative destinations could provide a more genuine and budget-friendly experience.

Best time to go to Cape Girardeau

Cape Girardeau experiences its lowest average temperature in January, at 34.9°F (1.6°C), while July is the hottest month, with an average temperature of 79.2°F (26.2°C). April is usually the wettest month. April, June, and July are the peak travel months in Cape Girardeau, attracting a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light rainfall. On the other hand, January, October, and December tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.

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