Hotels in Panacea

October 2026
November 2026

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Check prices for these dates

This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Where to stay in Panacea?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Panacea on Hotels.com. These Panacea hotels consistently deliver on quality, location and traveller experience. Last updated on 18 September 2026.

1. The Panacea Motel

The Panacea Motel
Panacea
₹11,432
₹12,747 total
includes taxes & fees
21 Sept - 22 Sept
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
₹10,670
₹11,897 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
Crawfordville
₹11,129
₹12,793 total
includes taxes & fees
11 Oct - 12 Oct
Wildwood Inn

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
₹8,564
₹9,550 total
includes taxes & fees
24 Sept - 25 Sept
The Lodge at Wakulla Springs

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
₹12,162
₹17,052 total
includes taxes & fees
1 Oct - 2 Oct
St James Bay Golf & Pickleball Resort

6. Franklin Inn

Franklin Inn
Carrabelle
₹9,024
₹9,971 total
includes taxes & fees
20 Sept - 21 Sept
Franklin Inn

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
₹10,104
₹11,165 total
includes taxes & fees
1 Oct - 2 Oct
The Old Carrabelle Hotel

8. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
₹13,243
₹14,633 total
includes taxes & fees
1 Oct - 2 Oct
The Moorings Hotel and Marina
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Go beyond your typical stay in Panacea

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Our prices for hotels in Panacea are cheapest in February

Price trends for hotels in Panacea

Pricing is based on two traveller single night rates
View properties in September

September

High 30°C / low 23°C. Sunny most days.
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23°
27°
18°
22°
13°
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11°
17°
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25°
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Monthly weather averages (˚C)

Top landmarks in Panacea

Alligator Point Beach

8.8/10 (10 reviews)
When the beach is calling your name, you might want to head down to Alligator Point Beach, located 4.5 mi (7.2 km) from central Alligator Point. Enjoy the sunset by the shore at Wilson Beach.
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Bald Point State Park

8.6/10 (20 reviews)
Bald Point State Park is 1.7 mi (2.7 km) from central Alligator Point, why not stop by during your stay.
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Mashes Sand Beach

8.8/10 (3 reviews)
If being by the water is a major draw, Mashes Sand Beach is a spot you might want to check out, located 5.1 mi (8.2 km) from central Panacea. If you want to continue walking by the waves, head to Shell Point Beach, Alligator Point Beach, and Wilson Beach.
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Wilson Beach

Whether you want to collect beach glass or watch the sunset, Wilson Beach is a spot you might want to check out, located 7.4 mi (11.9 km) from central Panacea. Enjoy the sunset by the shore at Alligator Point Beach.
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beach near Alligator Point

When the beach is calling your name, you might want to head down to beach near Alligator Point, located 2.7 mi (4.4 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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beach near Summer Camp Beach

Whether you want to collect beach glass or watch the sunset, beach near Summer Camp Beach is a spot you might want to check out, located 10.3 mi (16.6 km) from central Panacea. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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Public Beach Access

Public Beach Access is 2.3 mi (3.7 km) from central Alligator Point, why not stop by during your stay. Want to stretch your legs some more? Head to Alligator Harbor Aquatic Preserve, located nearby.
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beach near Alligator Point Marina

When the beach is calling your name, you might want to head down to beach near Alligator Point Marina, located 3 mi (4.8 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants as well as sights like Bald Point State Park and Wilson Beach. All are within a secluded setting.

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A sunset over a calm body of water with silhouettes of birds flying and a distant tree line.

Frequently Asked Questions

Can I book a refundable accommodation in Panacea?

If you're looking for the flexibility to change your travel plans to Panacea, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Panacea if I want a vacation home instead of a traditional hotel?

If you want a good alternative to a hotel, browse our selection of 175 vacation homes. In addition, there are 18 apartments and 10 condos.

What will the weather in Panacea be like during my visit?

July and August are typically the warmest months in Panacea when the average temp is 81°F. January and February are the coldest months when the average temperature is 58°F. August and July are the months with the most rain.

Why should I book my Panacea hotel through Hotels.com?

There are lots of reasons to book your Panacea trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Panacea

Discover Panacea, Florida, a charming coastal haven celebrated for its pristine beaches and unspoilt natural beauty. This tranquil destination offers a delightful escape with its serene shoreline, inviting nature trails, and a welcoming community. Wander along its sandy beaches, breathe in the fresh sea air, and enjoy the peaceful ambiance that sets the perfect scene for relaxation. Panacea's blend of coastal allure and verdant landscapes makes it an ideal retreat for nature lovers and those seeking a slice of seaside paradise.

Discover great hotels near Panacea

Panacea hotels offer a mix of modern and cosy styles, often featuring free cancellation and competitive room rates. Options range from budget motels to more refined hotels, ensuring a suitable stay for every traveller. Here are some of our travelers' favorite hotels near Panacea:

  1. Best Western Wakulla Inn & Suitesopens in new window: This 3-star lodging boasts an impressive guest rating and offers adventure sports and onsite recreational activities such as cycling, hiking, kayaking, sailing, and snorkelling. Designed with the leisure traveller in mind, the property features distinctive architectural design and a curated experience that promises a smooth, high-quality journey. Guests celebrate the welcoming atmosphere, the perfect room settings, and a sumptuous breakfast that elevates the stay to a memorable experience.
  2. Wildwood Innopens in new window: With a 3.0-star rating and an excellent guest rating, this hotel presents a delightful retreat for leisure travellers seeking a distinctive and engaging holiday experience. The property offers a range of adventure sports and recreational activities including hiking, boat tours, kayaking, sailing, and mountain biking. Guests mention the efficient service, clean rooms, and delightful breakfast, all of which contribute to a seamless and enjoyable experience.
  3. St James Bay Golf & Pickleball Resortopens in new window: Rated at 3.5-stars with a high guest rating, this hotel caters to leisure travellers looking for an exceptional destination with a focus on golf and adventure sports. The property offers a variety of activities including snorkelling, windsurfing, waterskiing, boat tours, and sailing. With its charming cottages, exquisite restaurant, and a unique golfing experience, this property delivers a captivating and well-curated stay designed for those seeking comfort and a distinctive holiday experience.

Where to stay in and around Panacea

When visiting Panacea, Florida, consider staying in Saint Teresa, Alligator Point, or Crawfordville. Saint Teresa offers serene beaches, while Alligator Point is perfect for nature enthusiasts. Crawfordville is excellent for families, boasting hiking, wildlife, and friendly locals. For first-time visitors, Crawfordville is the best choice due to its diverse activities and family-friendly atmosphere.

  1. Saint Teresaopens in new window: Saint Teresa is a sought-after spot offering a blend of local charm and modern comforts. With a relaxed atmosphere, it attracts those who appreciate a calm retreat while still being close to a range of cultural attractions. Its setting makes it ideal for travellers looking for a peaceful stay with easy access to quaint shopping and dining areas. The town’s well-kept public spaces and friendly vibe make it a great base for exploring nearby must-see places, ensuring a cosy and memorable experience.
  2. Alligator Pointopens in new window: Alligator Point stands out as a unique destination with a distinct coastal allure. It offers a laid-back environment perfect for visitors who enjoy the seaside and the charm of waterfront living. Here, you can easily access local dining and boating opportunities, enhancing your stay with easy-going, leisure-focused activities. Its local attractions create a relaxed ambience, giving you a taste of the area's authentic coastal life.
  3. Crawfordvilleopens in new window: Crawfordville is a delightful destination known for its natural beauty and family-friendly vibe. With a range of affinities such as nature, hiking, hunting, and wildlife, it is perfect for those who love the outdoors and a quieter pace of life. The community is friendly, and the local forests and boating options offer plenty of opportunities for a relaxing and engaging stay. This spot is a must for travellers seeking a blend of outdoor adventures and a warm, inviting atmosphere.

Things to do in Panacea

Panacea is a true haven for nature lovers, boasting stunning beaches, lush forests, and serene lakes. Here, you can embark on exciting boat trips to spot playful dolphins, cast a line for fishing, or hike through picturesque trails. As the sun sets, enjoy breathtaking views that will leave you enchanted. It’s an ideal getaway for those seeking relaxation and outdoor fun!

  • Shell Point Beachopens in new window – Enjoy a visit to Shell Point Beach, where the gentle sound of the waves and the vast expanse of sand invite you to relax and enjoy nature. This coastal spot is ideal for a leisurely walk along the shore or simply soaking in the seaside ambience.
  • Wakulla Springs State Parkopens in new window – Discover the natural splendour of Wakulla Springs State Park, a national park that offers a close encounter with Florida’s scenic water bodies. Whether you’re interested in local flora or a refreshing dip, the park provides a peaceful retreat in a pristine environment.
  • St. Marks National Wildlife Refugeopens in new window – Explore St. Marks National Wildlife Refuge, a reserve preserve where you can witness diverse wildlife and enjoy the tranquillity of unspoiled nature. This spot is perfect for anyone looking to observe birds and other native species in their natural habitat.
  • Ochlockonee River State Parkopens in new window – Visit Ochlockonee River State Park, another national park that features the meandering Ochlockonee River and its surrounding natural beauty. It offers opportunities to explore the riverbanks and enjoy a serene day out in the great outdoors.
  • Alligator Point Beachopens in new window – Head to Alligator Point Beach for a day by the sea, where the beach setting is ideal for sunbathing, a picnic, or an evening walk. The location is known for its clean sands and inviting waters, making it a delightful spot to unwind.

4 tips for savvy savings when booking a hotel in Panacea

  1. Book for the cheapest times: The most budget-friendly times to visit Panacea are in January, July, and December, when hotel prices are lower. For a truly enriching experience, a stay of at least 2 to 3 days is recommended to fully appreciate the area's key landmarks, historical sites, and cultural attractions. Visitors can enjoy the serene beaches, observe dolphins, savour delicious seafood, and unwind in secluded spots. Additionally, the region offers opportunities for fishing, nature exploration, wildlife observation, and breathtaking sunsets, making it great value for money, especially for those travelling on a budget. With prices potentially dropping during these months, it's an ideal time to explore the beauty of Panacea.
  2. Look for last-minute deals on Hotels.com: At Hotels.com, you may discover attractive hotel deal options for Panacea by exploring Dealsopens in new window, where discounted offers await, and the Last-Minute Deals section, which could reveal opportunities for last-minute getaways. Moreover, by enabling alerts, you're more likely to be informed when rooms become available or prices drop. The app's Smart Shopping feature, a handy comparison tool, lets travellers compare hotel prices and amenities efficiently, ensuring you remain updated on the best deal for your perfect hotel stay in Panacea.
  3. Be flexible with dates: Prices may fluctuate due to factors such as the hotel's location, star rating, and time of year, so having some flexibility with your travel dates could help you find a more favourable rate at the Panacea hotel. For those in search of distinctive accommodations, boutique hotels often provide a more personalised experience and occasionally represent a better value. When you book through Hotels.com, we will inform you if the price for your chosen dates is above or below the average. If the price is on the higher end, we may suggest alternative dates that could lead to more affordable options.
  4. Consider your location: Staying nearer to key attractions or city centres may offer convenience, but it often comes with higher costs. For more affordable options, consider hotels in less central areas or neighbourhoods, striking a balance between price and ease of access to your intended destinations. You might also look into independent hotels located further out, which can provide a more authentic and usually tend to be cheaper experience.

Best time to go to Panacea

Panacea experiences its lowest average temperature in January, at 53.6°F (12.0°C), while July to August are the hottest months, with an average temperature of 81.7°F (27.6°C). August tends to be the wettest month. The peak travel months to visit Panacea are April, June, and July, which see a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light to moderate rainfall. In contrast, October to December are ideal if you're looking for a calmer vacation, marked by light rainfall and mostly sunny conditions.

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