Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Panama City on Hotels.com. These Panama City hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in Panama City
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Hotel Riu Plaza Panama
Hotel Riu Plaza PanamaBella Vista
9.0 out of 10, Wonderful, (5,763 reviews)
$129 nightly
The price is $142
Aug 17 - Aug 18
Total with taxes and fees

JW Marriott Panama
JW Marriott PanamaSan Francisco
9.0 out of 10, Wonderful, (1,011 reviews)
$263 nightly
The price is $290
Aug 15 - Aug 16
Total with taxes and fees

The Executive Hotel
The Executive HotelBella Vista
9.2 out of 10, Wonderful, (1,194 reviews)
$89 nightly
The price is $98
Aug 11 - Aug 12
Total with taxes and fees

Megapolis Hotel Panamá
Megapolis Hotel PanamáSan Francisco
8.4 out of 10, Very Good, (1,616 reviews)
$229 nightly
The price is $252
Jul 26 - Jul 27
Total with taxes and fees

Hyatt Regency Panama City
Hyatt Regency Panama CityBella Vista
9.6 out of 10, Exceptional, (382 reviews)
$171 nightly
The price is $188
Aug 20 - Aug 21
Total with taxes and fees

Riande Urban Hotel
Riande Urban HotelBella Vista
8.8 out of 10, Excellent, (1,028 reviews)
$107 nightly
The price is $118
Aug 21 - Aug 22
Total with taxes and fees

Las Americas Golden Tower Panama
Las Americas Golden Tower PanamaSan Francisco
9.0 out of 10, Wonderful, (1,064 reviews)
$146 nightly
The price is $160
Jul 26 - Jul 27
Total with taxes and fees

Principe Hotel and Suites
Principe Hotel and SuitesBella Vista
9.0 out of 10, Wonderful, (1,978 reviews)
$57 nightly
The price is $62
Jul 26 - Jul 27
Total with taxes and fees

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn HotelSan Francisco
9.4 out of 10, Exceptional, (2,213 reviews)
$103 nightly
The price is $114
Jul 30 - Jul 31
Total with taxes and fees

Aloft by Marriott Panama
Aloft by Marriott PanamaSan Francisco
8.8 out of 10, Excellent, (1,005 reviews)
$119 nightly
The price is $131
Aug 14 - Aug 15
Total with taxes and fees

Waymore Hotel Spa & Casino
Waymore Hotel Spa & CasinoBella Vista
9.0 out of 10, Wonderful, (1,025 reviews)
$97 nightly
The price is $108
Aug 8 - Aug 9
Total with taxes and fees

Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta PacificaSan Francisco
9.6 out of 10, Exceptional, (1,276 reviews)
$108 nightly
The price is $119
Aug 2 - Aug 3
Total with taxes and fees

Novotel Panama City
Novotel Panama CityBella Vista
9.2 out of 10, Wonderful, (1,248 reviews)
$120 nightly
The price is $132
Aug 23 - Aug 24
Total with taxes and fees

Decapolis Hotel Panama City
Decapolis Hotel Panama CitySan Francisco
8.6 out of 10, Excellent, (1,715 reviews)
$125 nightly
The price is $137
Jul 29 - Jul 30
Total with taxes and fees

Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza MallSan Francisco
9.0 out of 10, Wonderful, (1,008 reviews)
$118 nightly
The price is $130
Aug 8 - Aug 9
Total with taxes and fees

TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá CentroBella Vista
9.0 out of 10, Wonderful, (1,007 reviews)
$100 nightly
The price is $110
Aug 23 - Aug 24
Total with taxes and fees

Sheraton Grand Panama
Sheraton Grand PanamaSan Francisco
8.6 out of 10, Excellent, (1,002 reviews)
$171 nightly
The price is $188
Aug 3 - Aug 4
Total with taxes and fees

Hilton Panama
Hilton PanamaBella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
$245 nightly
The price is $270
Aug 16 - Aug 17
Total with taxes and fees

Marriott Executive Apartments Panama City, Finisterre
Marriott Executive Apartments Panama City, FinisterreBella Vista
8.8 out of 10, Excellent, (731 reviews)
$127 nightly
The price is $139
Aug 16 - Aug 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Jul 31 - Aug 2

9.0 out of 10, Wonderful, (5,763 reviews)
$272 off
$146 nightly
The price is $320
Total with taxes and fees
Showing deals for:Aug 23 - Aug 24

9.0 out of 10, Wonderful, (5,763 reviews)
$120 off
$129 nightly
The price is $142
Total with taxes and fees
Check out pet-friendly hotels in Panama City

8.6 out of 10, Excellent, (2623)
$110 nightly
The price is $121
Aug 16 - Aug 17
Total with taxes and fees
You may also like hotels with pools in Panama City

9.0 out of 10, Wonderful, (5763)
$129 nightly
The price is $142
Aug 17 - Aug 18
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Panama City
Pet friendly
Top neighborhoods in Panama City

Casco Viejo
Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

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Open Photo by My World
Bella Vista
Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

El Cangrejo
El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

Obarrio
Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

Punta Pacifica
Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.
Learn more about Panama City
Wander through the historic Casco Viejo district, marveling at colorful colonial buildings and bustling plazas. Cruise through the famous Panama Canal, watching massive ships navigate the ingenious locks system.

Check out reviews of Panama City hotels guests love

Hotel Riu Plaza Panama
10/10 Excellent
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