Hotels in Defiance

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Check prices for these dates

Tonight
31 May - 1 Jun
Tomorrow
1 Jun - 2 Jun
Next weekend
6 Jun - 8 Jun
In two weeks
13 Jun - 15 Jun

Where to stay in Defiance?

Holiday Inn Express St. Louis West - O'Fallon by IHG
Exterior

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
8.4 out of 10, Very good, (705)
The price is ₹10,099
₹11,912 total
includes taxes & fees
15 Jun - 16 Jun
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Defiance

August A. Busch Memorial Conservation Area

August A. Busch Memorial Conservation Area

If you like spending time outside, why not spend the afternoon at August A. Busch Memorial Conservation Area, a park located 30.2 mi (48.6 km) from the centre of St. Louis.

See properties in August A. Busch Memorial Conservation Area
August A. Busch Memorial Conservation Area

Learn more about Defiance

Defiance is well-known for its attractions such as Chandler Hill Vineyards and Sugar Creek Winery.

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Frequently asked questions

Can I book refundable accommodations in Defiance?
If you need the flexibility to change your plans to Defiance, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Defiance be like during my vacation?
July and August are typically the warmest months in Defiance when the average temp is 76°F. January and February are the coldest months when the average temperature is 38°F. May and April are the months with the most rain.
Why should I book my Defiance hotel through Hotels.com?
There are lots of reasons to book your Defiance trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.